Zinc-responsive necrolytic acral erythema

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Synonyms: NAE | Necrolytic acral erythema

A rare skin disease characterized initially by erythematous patches with superficial necrosis at later stages by hyperkeratotic plaques with a rim of dusky erythema of exclusively acral distribution with a predilection for the lower extremities and universal association with hepatitis C virus infection. Patients typically experience pruritus or pain. Serum zinc levels may or may not be decreased although oral zinc supplementation often improves the condition.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version May 2024

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Zinc-responsive necrolytic acral erythema?

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Clinical Trials

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