Male infertility due to globozoospermia

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Synonyms: Male infertility due to round-headed spermatozoa | Round-headed sperm syndrome

Male infertility due to globozoospermia is a male infertility due to sperm disorder characterized by the presence in sperm of a large majority of round-headed spermatozoa that lack the acrosome and have an aberrant nuclear membrane and midpiece defects. The acrosomeless spermatozoa is not able to penetrate the zona pellucida and thus fertilization failures even with intracytoplasmic sperm injection are frequent.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on Data version May 2024

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