Male infertility due to large-headed multiflagellar polyploid spermatozoa
Synonyms: Macrocephalic sperm head syndrome | Male infertility due to macrozoospermia
A rare male infertility due to a sperm disorder characterized by the presence in sperm of a very high percentage of spermatozoa with enlarged head irregular head shape multiple flagella and abnormal midpiece and acrosome. It is generally associated with severe oligoasthenozoospermia and a high rate of sperm chromosomal abnormalities (polyploidy aneuploidy).
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: //www.orphadata.org. Data version September 2023.
Newly diagnosed with
Male infertility due to large-headed multiflagellar polyploid spermatozoa?
Our RARE Concierge Services Guides are available to assist you by providing information, resources and connections as you navigate your rare disease journey.
Syndromes Without A Name (SWAN) Australia
Provide information, support and advocacy to families caring for a child with an undiagnosed or rare genetic condition.
For a list of clinical trials in this disease area, please click here.