PPARG-related familial partial lipodystrophy
Synonyms: FPLD3 | Familial partial lipodystrophy type 3 | PPARG-related FPLD
A rare familial partial lipodystrophy characterized by adult onset of distal lipoatrophy with gluteofemoral fat loss as well as increased fat accumulation in the face and trunk and visceral adiposity. Additional manifestations include diabetes mellitus atherogenic dyslipidemia eyelid xanthelasmas arterial hypertension cardiovascular disease hepatic steatosis acanthosis nigricans on axillae and neck hirsutism and muscular hypertrophy of the lower limbs.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
Newly diagnosed with
PPARG-related familial partial lipodystrophy?
Our RARE Concierge Services Guides are available to assist you by providing information, resources and connections as you navigate your rare disease journey.
Advocacy Organizations
Syndromes Without A Name (SWAN) Australia
Provide information, support and advocacy to families caring for a child with an undiagnosed or rare genetic condition.
Clinical Trials
For a list of clinical trials in this disease area, please click here.