Synonyms: BOS syndrome | Bohring syndrome | C-like syndrome | Oberklaid-Danks syndrome | Opitz trigonocephaly-like syndrome
A rare multiple congenital anomalies syndrome characterized by intrauterine growth retardation (IUGR) postnatal failure to thrive severe feeding difficulties microcephaly/trigonocephaly facial dysmorphism a recognizable upper limb posture and severe developmental delay. The upper limb posture consists of internal rotation of the shoulders flexion of the elbows ulnar deviation of wrists and/or metacarpophalangeal joints.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version May 2026
Newly diagnosed with
Bohring-Opitz syndrome?
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Advocacy Organizations
ASXL Rare Research Endowment Foundation
Our mission is to support research and education that lead to improved quality of life for individuals with ASXL syndromes.
PPP2CA Pathways
PPP2CA Pathways connects families, shares strength, and supports the research community in the search for answers to Houge-Janssens Syndrome type 3.
ReNU2 United
ReNU2 United fosters collaboration, supports families, raises awareness, and advances research into RNU2-2-related neurodevelopmental disease.
Uganda Alliance of Patients Organization
Supporting patients to access quality, safe and patient-centered healthcare services.
Wave of Support, Inc
Empowering those affected by bleeding disorders and other rare disease through advocacy, resources, education, and support
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Clinical Trials
For a list of clinical trials in this disease area, please click here.