Synonyms: ALSP | Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia | Autosomal dominant leukoencephalopathy with neuroaxonal spheroids | FPSG | Familial dementia, Neumann type | Familial progressive subcortical gliosis | GPSC | HDLS | Hereditary diffuse leukoencephalopathy with spheroids | POLD | Pigmentary orthochromatic leukodystrophy | Subcortical gliosis of Neumann
Hereditary diffuse leukoencephalopathy with axonal spheroids and pigmented glia is a rare autosomal dominant disease characterized by a complex phenotype including progressive dementia apraxia apathy impaired balance parkinsonism spasticity and epilepsy.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version September 2024
Newly diagnosed with
Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia?
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Advocacy Organizations
Alex, The Leukodystrophy Charity
Support and access to treatment for everyone living with leukodystrophy Provide support for those living with leukodystrophy, and their families/carers Raise awareness of leukodystrophy Improve best practice in prevention, diagnosis & treatment Support research initiatives
KIF1A.ORG
KIF1A.ORG is a global community dedicated to improving the lives of those affected by KIF1A Associated Neurological Disorder (KAND) and accelerating research to find a cure.
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Clinical Trials
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