Hypotrichosis-osteolysis-periodontitis-palmoplantar keratoderma syndrome

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Synonyms: HOPP syndrome | Hypotrichosis-osteolysis-periodontitis-palmoplantar hyperkeratosis syndrome | Hypotrichosis-striate palmoplantar hyperkeratosis-acroosteolysis-periodontitis syndrome | Hypotrichosis-striate palmoplantar keratoderma-acroosteolysis-periodontitis syndrome

Hypotrichosis-osteolysis-periodontitis-palmoplantar keratoderma syndrome is an extremely rare ectodermal dysplasia syndrome characterized by hypotrichosis universalis with mild to severe scarring alopecia acro-osteolysis onychogryphosis thin and tapered fingertips periodontitis and caries leading to premature teeth loss linear or reticular palmoplantar keratoderma and erythematous scaling psoriasis-like skin lesions on arms and legs. Lingua plicata and ventricular tachycardia have also been observed.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version June 2024

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