MAGIC syndrome

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MAGIC syndrome

Synonyms: Mouth and genital ulcers-inflamed cartilage syndrome

A rare autoinflammatory syndrome characterized by the presence of features of relapsing polychondritis and Behçet’s disease in the same individual. This includes cartilage inflammation of the ears nose throat and rib cage as well as recurrent oral and genital ulcers respectively. Patients may also present ocular involvement (in particular anterior uveitis or scleritis) arthritis fever colitis thrombophlebitis central nervous system vasculitis or in rare cases arterial aneurysms. Symptoms of polychondritis occur secondary to those of Behçet’s disease in the vast majority of cases.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on Data version March 2024

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Clinical Trials

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