Synonyms: Doose syndrome | EMAS | Epilepsy with myoclonic-astatic seizures | Epilepsy with myoclonic-atonic seizures | MAE | Myoclonic atonic epilepsy | Myoclonic-astatic epilepsy in early childhood
A rare childhood onset epilepsy syndrome characterized by multiple seizure types including myoclonic-atonic (MA) seizures that occur usually in previously healthy children.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version June 2026
Newly diagnosed with
Myoclonic-astatic epilepsy?
Our RARE Concierge Services Guides are available to assist you by providing information, resources and connections as you navigate your rare disease journey.
Advocacy Organizations
Access to Life NGO
Our mission is to improve the lives of people affected by genetic epilepsies by empowering patients and families, advancing access to diagnosis and treatment, supporting research, and advocating for equitable, patient-centered care in Ukraine in alignment with global rare disease standards.
Cookies4Cures
Funding research into rare pediatric diseases
Genetic Epilepsy Team Australia
Collaboration of research and care
MAST Genes Research Foundation
Connecting families and fueling research into microtubule-associated serine/threonine kinase (MAST) genetic mutations to improve the quality of life and develop therapies to support affected patients and families.
Mickie?s Miracles
To help families get into Level IV Pediatric Epilepsy Centers for diagnosis and treatment urgently -- and provide support to families for every season of the pediatric epilepsy journey.
Rare Epilepsy Network (REN)
Improving outcomes of people with rare epilepsies through an innovative collaborative infrastructure that drives urgent, patient-centered research, educaiton and advocacy.
ReNU2 United
ReNU2 United fosters collaboration, supports families, raises awareness, and advances research into RNU2-2-related neurodevelopmental disease.
SLC6A1 Connect
SLC6A1 Connect is a patient advocacy group dedicated to improving the lives of children and families affected by SLC6A1. SLC6A1 epileptic encephalopathy is a rare neurological condition in small children that causes seizures, severe movement and speech disorders and intellectual disability. Our group is led by and comprised of passionate and relentless parents of kids with SLC6A1. Our mission is to advance scientific research that will ultimately result in a disease modifying treatment.
Uganda Alliance of Patients Organization
Supporting patients to access quality, safe and patient-centered healthcare services.
Don't see your organization here. Let us know here.
Clinical Trials
For a list of clinical trials in this disease area, please click here.