Spinocerebellar ataxia type 3
Synonyms: Azorean disease of the nervous system | MJD | Machado disease | Machado-Joseph disease | Nigro-spino-dentatal degeneration with nuclear ophthalmoplegia | SCA3
Spinocerebellar ataxia type 3 (SCA3) also known as Machado-Joseph disease is the most common subtype of type 1 autosomal dominant cerebellar ataxia (ADCA type 1; see this term) a neurodegenerative disorder and is characterized by ataxia external progressive ophthalmoplegia and other neurological manifestations.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
Newly diagnosed with
Spinocerebellar ataxia type 3?
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Advocacy Organizations
KIF1A.ORG
KIF1A.ORG is a global community dedicated to improving the lives of those affected by KIF1A Associated Neurological Disorder (KAND) and accelerating research to find a cure.
National Ataxia Foundation
To accelerate the development of treatments and a cure while working to improve the lives of those living with Ataxia.
Clinical Trials
For a list of clinical trials in this disease area, please click here.