Synonyms: Systemic scleroderma
Systemic sclerosis (SSc) is a generalized disorder of small arteries microvessels and connective tissue characterized by fibrosis and vascular obliteration in the skin and organs particularly the lungs heart and digestive tract. There are two main subsets of SSc: diffuse cutaneous SSc (dcSSc) and limited cutaneous SSc (lcSSc) (see these terms). A third subset of SSc has also been observed called limited Systemic Sclerosis (lSSc) or systemic sclerosis sine scleroderma (see these terms).
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version December 2023
Newly diagnosed with
Our RARE Concierge Services Guides are available to assist you by providing information, resources and connections as you navigate your rare disease journey.
Children’s Cardiomyopathy Foundation
CCF's mission is to accelerate the search for causes and cures for pediatric cardiomyopathy through increased research, education, awareness, advocacy, and support to affected children and their families.
Heart of a Giant Foundation
The mission of the HGF is to achieve better health outcomes for heart diseases and related chronic health conditions in our communities and enhance the quality of life through health education, care support, and connection to community resources.
Help Hope Live
Help Hope Live assists individuals living with catastrophic injuries and illnesses to fundraise toward their medical expenses and related costs.
My Faulty Gene
My Faulty Gene is a nonprofit organization which provides information and assistance to any individual whose family medical history suggests genetic testing might be helpful in identifying an increased risk of disease due to a genetic mutation. We believe that everyone in need of genetic testing should have access to it.
National Scleroderma Foundation
Our mission is to advance medical research, promote disease awareness, and provide support and education to people with scleroderma, their families and support network.
To improve our understanding of rare and understudied autoimmune conditions
To raise awareness for Scleroderma by way of documentary films/videos, educating and inspiring support of research.
Scleroderma Foundation of California
Our mission is to EMPOWER the scleroderma community to live BETTER lives through programs dedicated to SUPPORT, EDUCATION, and RESEARCH
Scleroderma Research Foundation
The mission of the Scleroderma Research Foundation (SRF) is to fund and facilitate the most promising, highest quality research aimed at improved therapies and, ultimately, a cure for scleroderma.
UNITED FOR SCLERODERMA Foundation
To assist the newly diagnosed Scleroderma patients
For a list of clinical trials in this disease area, please click here.