Systemic sclerosis

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Systemic sclerosis

Synonyms: Systemic scleroderma

Systemic sclerosis (SSc) is a generalized disorder of small arteries microvessels and connective tissue characterized by fibrosis and vascular obliteration in the skin and organs particularly the lungs heart and digestive tract. There are two main subsets of SSc: diffuse cutaneous SSc (dcSSc) and limited cutaneous SSc (lcSSc) (see these terms). A third subset of SSc has also been observed called limited Systemic Sclerosis (lSSc) or systemic sclerosis sine scleroderma (see these terms).

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on Data version December 2023

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Systemic sclerosis?

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Advocacy Organizations

My Faulty Gene

My Faulty Gene is a nonprofit organization which provides information and assistance to any individual whose family medical history suggests genetic testing might be helpful in identifying an increased risk of disease due to a genetic mutation. We believe that everyone in need of genetic testing should have access to it.

Clinical Trials

For a list of clinical trials in this disease area, please click here.