Vegetative pyoderma gangrenosum
Synonyms: Granulomatous pyoderma gangrenosum
A rare subtype of pyoderma gangrenosum disease characterized by a solitary erythematous ulcerated plaque which lacks the violaceous border typically present in classic pyoderma gangrenosum usually affecting individuals who are otherwise healthy. Histologically the lesion presents a central layer containing neutrophilic inflamation surrounded by a palisade of histiocytes which are rimmed by a lymphocytic infiltrate. In comparison with the other variants of pyoderma gangrenosum this subtype usually shows a good response to less aggressive treatments and underlying systemic disorders are less frequently associated. It is considered the most benign and uncommon clinical variant of pyoderma gangrenosum.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: //www.orphadata.org. Data version September 2023.
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Ukrainian Association of Pediatric Immunology
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