Gestational Pemphigoid

Pemphigoid gestationis


Type of disease: Rare conditions

Pemphigoid gestationis (PG), also known as gestational pemphigoid or herpes gestationis, is an autoimmune skin disorder associated with pregnancy. Signs and symptoms of the disorder typically present during the second or third trimester of pregnancy, but it may occur at any time during pregnancy or anywhere up to six weeks after giving birth. Although the signs and symptoms are variable, a red, itchy rash with blisters is common. The rash may occur in different parts of the body, but usually develops near the belly button and/or the arms and legs. The condition is caused by the production of antibodies that attack the person’s body, leading to damage and consequently blister formation. Treatment generally involves systemic corticosteroids.  Source: Genetic and Rare Diseases Information Center (GARD), supported by ORDR-NCATS and NHGRI.

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