Synonyms: Dup(11)p(15.4) | Trisomy 11p15.4
A rare partial autosomal trisomy/tetrasomy characterized by obesity global developmental delay and intellectual disability facial dysmorphism (synophrys high-arched eyebrows large posteriorly rotated ears upturned nose long smooth philtrum overbite and high palate) large hands and limb hypotonia. Additional features include seizures and behavioral abnormalities.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2026
Newly diagnosed with
11p15.4 microduplication syndrome?
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Advocacy Organizations
3:1 Neuropsychology Consultants, PLLC
Center For Ichthyosis Related Members Foundation India
To preserve and protect the health of and to relieve persons affected by ichthyosis and any associated condition. To enabled the basic knowledge of medical professionals and the general public on the subject of ichthyosis and its implications for the family. To promote research into the management of ichthyosis and to publish the useful results thereof, and to support organizations promoting res
Malaysian Rare Disorders Society
1. Provide support to individuals and families affected with Rare Disorders. 2. Develop strategies and programs to raise public and professional 3. Ensure Human Rights of access to healthcare education, job opportunities are upheld. 4. Participate in the formulation and implementation national policies in Malaysia related to person with rare disorders and rare disorders
PPP2CA Pathways
PPP2CA Pathways connects families, shares strength, and supports the research community in the search for answers to Houge-Janssens Syndrome type 3.
Rare Chromosome Disorder Support Group – Unique
Through sharing knowledge and lived experience, Unique helps families and professionals navigate the world of chromosome and gene disorders
Youngtimers Inc.
Youngtimers is dedicated to providing support and resources for families affected by autosomal dominant Alzheimer's disease.
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Clinical Trials
For a list of clinical trials in this disease area, please click here.