Synonyms: Craniocerebellocardiac dysplasia | Ritscher-Schinzel syndrome
Cranio-cerebello-cardiac (3C) syndrome is a rare multiple congenital anomalies syndrome characterized by craniofacial (prominent occiput and forehead hypertelorism ocular coloboma cleft palate) cerebellar (Dandy-Walker malformation cerebellar vermis hypoplasia) and cardiac (tetralogy of Fallot atrial and ventricular septal defects) anomalies (see these terms).
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2026
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3C syndrome?
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Advocacy Organizations
Dandy Walker Institute
research genetic testing and finding cures to improve treatment outcomes
PPP2CA Pathways
PPP2CA Pathways connects families, shares strength, and supports the research community in the search for answers to Houge-Janssens Syndrome type 3.
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Clinical Trials
For a list of clinical trials in this disease area, please click here.