Benign hereditary chorea

Synonyms: BHC | Benign familial chorea

A rare genetic movement disorder characterized by early-onset very slowly progressive choreiform movements that may involve variable parts of the body typically aggravated by stress or anxiety in various members of a family. Additional variable manifestations include hypotonia often resulting in psychomotor delay (including gait disturbances) and dysarthria as well as myoclonus dystonia behavioral symptoms (ADHD obsessive-compulsive disorder) learning difficulties (particularly in writing) and spasticity with hyperreflexia and/or flexor/extensor plantar reflexes.