Synonyms: BIMSE
Benign infantile focal epilepsy with midline spikes and waves during sleep is a rare infantile epilepsy syndrome characterized by age of onset between 4 and 30 months partial sporadic seizures presenting with motion arrest staring cyanosis and less common automatisms and lateralizing signs and characteristic interictal sleep EEG changes consisting of a spike followed by a bell-shaped slow wave in the midline region.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2026
Newly diagnosed with
Benign infantile focal epilepsy with midline spikes and waves during sleep?
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Advocacy Organizations
Genetic Epilepsy Team Australia
Collaboration of research and care
Rare Epilepsy Network (REN)
Improving outcomes of people with rare epilepsies through an innovative collaborative infrastructure that drives urgent, patient-centered research, educaiton and advocacy.
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Clinical Trials
For a list of clinical trials in this disease area, please click here.