Fetal trimethadione syndrome
A drug-related embryofetopathy that can occur when an embryo/fetus is exposed to trimethadione and that is characterized by pre- and post-natal growth retardation intellectual deficit developmental and speech delay craniofacial anomalies (with some similarities to those seen in fetal valproate syndrome) and less commonly cleft palate malformations of the heart urogenital system and limbs. Trimethadione is an antiepileptic drug that has been removed from the market in Europe and is no longer used much in other countries due to teratogenicity and potential side effects.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version March 2024
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Fetal trimethadione syndrome?
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