Synonyms: GIST | Gastrointestinal stromal sarcoma
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal neoplasm of the gastrointestinal (GI) tract typically presenting in adults over the age of 40 (mean age 63) and only rarely in children in various regions of the GI tract most commonly the stomach or small intestine but also less commonly in the esophagus appendix rectum and colon. GISTs can be asymptomatic or present with various non-specific signs depending on the location and size of tumor such as loss of appetite anemia weight loss fatigue abdominal discomfort or fullness nausea vomiting as well as an abdominal mass blood in stool and intestinal obstruction. GISTs can also be seen in familial syndromes such as Carney triad and neurofibromatosis type 1.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2026
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Gastrointestinal stromal tumor?
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Advocacy Organizations
Life Raft Group
The Life Raft Group is committed to enhancing the survival and quality of life for people living with Gastrointestinal Stromal Tumor (GIST), and other rare diseases, through patient-powered research, education and empowerment, and global advocacy efforts.
accessia health
Accessia Health, a national charitable patient assistance organization, is dedicated to eliminating healthcare barriers for people with rare or chronic health conditions. Comprehensive services include personalized case management, financial assistance, education, and legal aid support. Our flexible funding model goes beyond copays, allowing individuals to pay for other essential medical expenses
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Clinical Trials
For a list of clinical trials in this disease area, please click here.