Synonyms: Anti-K HDN | Maternal anti-Kell alloimmunization
A rare hematologic disease characterized by the transfer of maternal alloantibodies against red blood cell antigens of the Kell family to a fetus positive for this antigen across the placental barrier causing suppression of erythropoiesis with reticulocytopenia and anemia as well as alloimmune hemolysis. Severe anemia may lead to hydrops fetalis. Significant hyperbilirubinemia is rare in this condition.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2026
Newly diagnosed with
Hemolytic disease of the newborn with Kell alloimmunization?
Our RARE Concierge Services Guides are available to assist you by providing information, resources and connections as you navigate your rare disease journey.
Advocacy Organizations
The Allo Hope foundation
Our goal is to prevent harm, still birth and infant death cause by alloimmunization and HDFN (hemolytic disease of the fetus and newborn.) We are dedicated to providing patient advocacy, support and education while promoting research and improving healthcare practices for the condition.
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Clinical Trials
For a list of clinical trials in this disease area, please click here.