A genetic condition characterized by hereditary susceptibility to breast and/or ovarian cancer. It can be defined using family history criteria or through identification of germline pathogenic variants (GPVs) in clinically validated HBOC genes. However the genetic basis of about half of clinical HBOC is currently unknown or unexplained by single-gene variants and approximately half of individuals who harbour PVs in HBOC genes do not have a suggestive family history.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2026
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Hereditary breast and/or ovarian cancer syndrome?
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Advocacy Organizations
FELIS HEALTHCARE FOUNDATION INC
The mission is to provide free health care services, education, and training to the most vulnerable, poorest, and underserved.The vision is ever-increasing access to medical treatment, better education, and nutrition, especially for those unable to pay for the necessary products and services.This approach helps us transform the lives of millions of people and address data gaps on different issues,
Speaking on Cancer Patient Advocacy
We seek to educate all on cancer from the importance of self-advocacy and how to go about doing that, how to advocate for loved ones and friends with cancer, how to work with fellow employees diagnosed with cancer, the basics of cancer, and much more.
The Assistance Fund
The Assistance Fund (TAF) is an independent charitable patient assistance organization that helps patients and families facing high medical out-of-pocket costs by providing financial assistance for their copayments, coinsurance, deductibles, and other health-related expenses.
Unfixed
Unfixed produces media that elevates stories of people living with chronic illness, rare disease and disability. The Unfixed portfolio of projects demonstrates that living well is not about eradicating our wounds and weaknesses but understanding how they complete our identities and equip us to help others. Current and past productions include multiple mini-series, a podcast and feature film.
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Clinical Trials
For a list of clinical trials in this disease area, please click here.