High altitude pulmonary edema

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Synonyms: HAPE

A rare pulmonary condition characterized by non-cardiogenic pulmonary edema occurring in otherwise healthy individuals within days of an ascent above 2500-3000 m. Early symptoms include exertional dyspnea non-productive cough chest tightness and reduced exercise performance followed by dyspnea at rest and possibly orthopnea as well as gurgling in the chest and pink frothy sputum in advanced cases. Clinical signs are cyanosis tachypnea tachycardia crackles or wheezing and elevated body temperature (generally not exceeding 38.5°C). Signs of concomitant high-altitude cerebral edema may also be observed. Chest x-rays typically show patchy opacities predominantly in the right middle lobe.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version June 2024

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