A rare subtype of indolent systemic mastocytosis characterized by isolated bone marrow involvement without skin lesions low burden of neoplastic mast cells and often normal or near normal serum tryptase levels. The KIT D816V mutation is present in the majority of cases.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2026
Newly diagnosed with
Isolated bone marrow mastocytosis?
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Advocacy Organizations
Super T’s Mast Cell Foundation
To increase awareness through resources, education and support for the mast cell diseases community, while also providing financial assistance to patients.
The Mast Cell Disease Society (TMS)
We are dedicated to providing multi-faceted support to patients, families and medical professionals in our community and to leading the advancement of knowledge and research in mast cell diseases through education, advocacy and collaboration.
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Clinical Trials
For a list of clinical trials in this disease area, please click here.