Limbal stem cell deficiency
A rare corneal disorder characterized by dysfunction and/or insufficient quantity of corneal limbal stem cells leading to impaired self-renewal of the corneal epithelium and resulting in epithelial breakdown corneal conjunctivalization and neovascularization chronic inflammation persistent epithelial defects and scarring. Patients usually present with ocular redness decreased vision photophobia foreign body sensation tearing and pain. The condition may be genetic idiopathic or acquired (in the context of inflammation infection trauma or ocular surface tumors).
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: //www.orphadata.org. Data version October 2023.
Newly diagnosed with
Limbal stem cell deficiency?
Our RARE Concierge Services Guides are available to assist you by providing information, resources and connections as you navigate your rare disease journey.