Synonyms: FPLD6 | LIPE-related FPLD
A rare genetic lipodystrophy characterized by abnormal subcutaneous fat distribution resulting in excess accumulation of fat in the face neck shoulders axillae trunk and pubic region and loss of subcutaneous fat from the lower extremities. Variable common additional features are progressive adult onset myopathy insulin resistance diabetes hypertriglyceridemia hepatic steatosis and vitiligo.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2026
Newly diagnosed with
LIPE-related familial partial lipodystrophy?
Our RARE Concierge Services Guides are available to assist you by providing information, resources and connections as you navigate your rare disease journey.
Advocacy Organizations
Lipodystrophy United
Our mission is to provide an interactive community, facilitated support, and education for anyone affected by lipodystrophy. We serve as a resource to increase awareness in the general, medical, and insurance communities. We advocate for new patient diagnosis by assisting healthcare professionals in understanding trends, physical attributes, and clinical symptoms to aid treatment and research.
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Clinical Trials
For a list of clinical trials in this disease area, please click here.