Livedoid vasculopathy

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Synonyms: Livedo reticularis with summer ulcerations | Milian atrophie blanche | Segmental hyalinizing vasculitis

A rare vascular skin disease characterized by recurrent focal non-inflammatory thrombosis of dermal venulae predominantly of the lower extremities resulting in a cutaneous response manifested as pruritus and painful papules and erythematous plaques. The lesions evolve into hemorrhagic vesicles or bullae which rupture and turn into painful ulcers merging into reticulate confluent geometric and painful ulcerations. During a period of a few months the ulcerations change to porcelain-white atrophic scars with punctate telangiectasia (so-called atrophie blanche). In active disease lesions in different stages coexist.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on Data version June 2024

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Clinical Trials

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