Malan overgrowth syndrome
Synonyms: Sotos syndrome 2
A rare multisystemic genetic disorder characterized by a characteristic facial features with macrocephaly overgrowth in infancy intellectual disability and behavioral problems including anxieties and aggressiveness.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
Newly diagnosed with
Malan overgrowth syndrome?
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Advocacy Organizations
COMBINEDBrain Inc
COMBINEDBrain is a consortium for outcome measures and biomarkers for neurodevelopmental disorders. We are collaborating to cure rare, non-verbal brain disorders.
DDX3X Foundation
Our mission is to connect families, resources, and the medical community to advance research for a treatment or cure to DDX3X Syndrome. Our ultimate goal is to accelerate brain function in individuals affected by DDX3X Syndrome through advances in cell and gene therapy and pharmaceuticals.
Malan Syndrome Foundation
The mission of the Malan Syndrome Foundation is to improve the lives of individuals and families affected by Malan syndrome in the global community through support, outreach and research. We aim to provide a broad network of support to families affected by Malan syndrome and help advance access to a diagnosis, promote knowledge development, awareness and sharing of information, explore research pathways to treatments and cures, as well as enhance understanding of Malan syndrome and related disorders.
Moonshots for Unicorns
Curing single-gene disorders
Oklahoma Rare
Oklahoma Rare is a collaborative community started by 2 parents of children diagnosed with rare diseases (both experienced advocates with history of working in the developmental disability and rare disease communities) created to share resources, advocacy opportunities and connection within the Oklahoma Rare Disease community.
Project CASK
To fund research for treatment and/or a cure for CASK Gene Disorder
Syndromes Without A Name (SWAN) Australia
Provide information, support and advocacy to families caring for a child with an undiagnosed or rare genetic condition.
Clinical Trials
For a list of clinical trials in this disease area, please click here.