Synonyms: Manganese intoxication | Manganism
A rare disorder due to toxic effects characterized by a progressive permanent affliction of the extrapyramidal system with the globus pallidus and striatum as primary targets of neurotoxic effects. Symptoms include headache insomnia memory loss emotional instability hyperreflexia dystonia tremor speech disturbances and gait abnormalities. Individual factors like age gender genetics and pre-existing medical conditions appear to have a profound impact on manganese toxicity.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2026
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Manganese poisoning?
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Advocacy Organizations
The Assistance Fund
The Assistance Fund (TAF) is an independent charitable patient assistance organization that helps patients and families facing high medical out-of-pocket costs by providing financial assistance for their copayments, coinsurance, deductibles, and other health-related expenses.
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Clinical Trials
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