Manganese poisoning
Synonyms: Manganese intoxication | Manganism
A rare disorder due to toxic effects characterized by a progressive permanent affliction of the extrapyramidal system with the globus pallidus and striatum as primary targets of neurotoxic effects. Symptoms include headache insomnia memory loss emotional instability hyperreflexia dystonia tremor speech disturbances and gait abnormalities. Individual factors like age gender genetics and pre-existing medical conditions appear to have a profound impact on manganese toxicity.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
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Manganese poisoning?
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Advocacy Organizations
COMBINEDBrain Inc
COMBINEDBrain is a consortium for outcome measures and biomarkers for neurodevelopmental disorders. We are collaborating to cure rare, non-verbal brain disorders.
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Curing single-gene disorders
Project CASK
To fund research for treatment and/or a cure for CASK Gene Disorder
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The Assistance Fund (TAF) is an independent charitable patient assistance organization that helps patients and families facing high medical out-of-pocket costs by providing financial assistance for their copayments, coinsurance, deductibles, and other health-related expenses. We currently manage more than 80 disease programs, each of which covers all FDA-approved treatment for the disease named in the program. Since 2009, TAF has helped nearly 180,000 people access critical treatment for life-threatening, chronic, and rare diseases.
Clinical Trials
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