Marchiafava-Bignami disease

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Marchiafava-Bignami disease

Synonyms: MBD

A rare neurologic disease most prominently characterized by progressive demyelination and necrosis of the corpus callosum. It is in most cases associated with chronic alcoholism and malnutrition. Speed of onset and clinical presentation are very variable with a range of possible symptoms including dementia seizures gait abnormalities dysarthria aphasia athetosis as well as stupor and coma.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on Data version April 2024

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Marchiafava-Bignami disease?

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