Synonyms: Midline heart
A rare congenital non-syndromic heart malformation characterized by an atypical location of the heart in a central position in the thorax with the apex in the midline of the thorax. Atria are usually situs solitus whereas ventricles may be situs inversus. Various congenital heart anomalies and visceral situs inversus have also been associated.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2026
Newly diagnosed with
Mesocardia?
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Advocacy Organizations
Heart of a Giant Foundation
The mission of the HGF is to achieve better health outcomes for heart diseases and related chronic health conditions in our communities and enhance the quality of life through health education, care support, and connection to community resources.
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Clinical Trials
For a list of clinical trials in this disease area, please click here.