Neonatal hypoxic and ischemic brain injury

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Synonyms: HIE | Hypoxic and ischemic brain injury in the newborn | Hypoxic-ischemic encephalopathy | Perinatal hypoxia

A rare neonatal encephalopathy characterized by alterations in mental status ranging from irritability and decreased responsiveness to coma as well as abnormal primitive reflexes hypotonia seizures and abnormalities in feeding and respiration with an onset within the first hours of life. The condition is associated with high mortality. Long-term sequelae include a spectrum of signs and symptoms including behavioral deficits developmental delay learning disabilities cognitive impairment seizures visual and auditory dysfunction and cerebral palsy.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version July 2024

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Neonatal hypoxic and ischemic brain injury?

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Advocacy Organizations

Project CASK

VISION Project CASK believes in a world free of the life limitations and debilitating effects of CASK gene disorders. ​MISSION To accelerate breakthroughs in research to develop treatments and a cure for CASK gene disorders. ​VALUES Collaboration. Transparency. Urgency.

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Clinical Trials

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