Osteoradionecrosis of the mandible

Get in touch with RARE Concierge.

Contact RARE Concierge

A rare radiation-induced disorder characterized by exposed irradiated bone that fails to heal over a period of three months without evidence of persisting or recurrent tumor. Patients present with pain dysesthesia dysgeusia fetor oris trismus ulceration or necrosis of the mucosa with exposure of necrotic bone and local suppuration. Complications include pathological fractures formation of intra- or extra-oral fistulae and infection. MRI shows cortical destruction abnormal bone marrow signal and irregular contrast enhancement.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version July 2024

Newly diagnosed with
Osteoradionecrosis of the mandible?

Our RARE Concierge Services Guides are available to assist you by providing information, resources and connections as you navigate your rare disease journey.

Get Concierge Help

Clinical Trials

For a list of clinical trials in this disease area, please click here.