Pediatric-onset Graves disease

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Pediatric-onset Graves disease

Synonyms: Pediatric-onset Basedow disease

A rare endocrine disease characterized by the presence of serum autoantibodies against thyroid-stimulating hormone receptors leading to increased thyroid hormone production and secretion causing diffuse toxic goiter. Patients present in childhood with signs of thyrotoxicosis (such as tachycardia weight loss hand tremor and sweating) diffuse enlargement of the thyroid gland and orbitopathy. Additional signs and symptoms include decreased academic and athletic performance accelerated growth restlessness fatigue sensitivity to heat and amenorrhea among others.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: // Data version October 2023.

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Pediatric-onset Graves disease?

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