Synonyms: Prader-Labhart-Willi syndrome
A rare genetic neurodevelopmental syndrome characterized by hypothalamic-pituitary dysfunction with severe hypotonia and feeding deficits during the neonatal period followed by an excessive weight gain period with hyperphagia with a risk of severe obesity during childhood and adulthood learning difficulties deficits of social skills and behavioral problems or severe psychiatric problems.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version March 2026
Newly diagnosed with
Prader-Willi syndrome?
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Advocacy Organizations
Indian Prader Willi Syndrome Association India
Awareness, support, patient Advocacy, genetic testing, d
International Prader-Willi Syndrome Organisation
IPWSO's mission is to unite the global PWS community to collectively find solutions to the challenges of the syndrome and to support and advocate for people with PWS and their families, PWS associations, and professionals who work with people with PWS.
Prader-Willi Syndrome Association USA
To enhance the quality of life of and empower those affected by Prader-Willi syndrome.
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Clinical Trials
For a list of clinical trials in this disease area, please click here.