Precursor B-cell acute lymphoblastic leukemia

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Synonyms: B-ALL | Precursor B-cell acute lymphoblastic leukemia/lymphoma | Precursor B-cell acute lymphocytic leukemia | Precursor B-cell acute lymphocytic leukemia/lymphoma

A rare acute lymphoblastic leukemia characterized by infiltration of bone marrow and peripheral blood by small to medium-sized blast cells typically positive for the B-cell markers CD19 cCD79a and cCD22. Predilection sites for extramedullary involvement are the central nervous system lymph nodes spleen liver and testes. Patients present with evidence of bone marrow failure (i. e. thrombocytopenia anemia and/or neutropenia) and variable leukocyte count as well as lymphadenopathy hepatomegaly splenomegaly bone pain and arthralgias.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version July 2024

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