Pressure-induced localized lipoatrophy

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Synonyms: Lipoatrophia semicircularis | Semicircular lipoatrophy

Pressure-induced localized lipoatrophy is a rare acquired localized lipodystrophy characterized by band-like horizontal asymptomatic lipoatrophic depressions with clinically normal overlying skin usually involving the anterolateral aspect of the thighs. An identifiable history of the repeated mechanical microtrauma due to occupational or postural habits is present.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2026

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Pressure-induced localized lipoatrophy?

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Advocacy Organizations

Lipodystrophy United

Our mission is to provide an interactive community, facilitated support, and education for anyone affected by lipodystrophy. We serve as a resource to increase awareness in the general, medical, and insurance communities. We advocate for new patient diagnosis by assisting healthcare professionals in understanding trends, physical attributes, and clinical symptoms to aid treatment and research.

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Clinical Trials

For a list of clinical trials in this disease area, please click here.