Primary hypereosinophilic syndrome
Synonyms: Clonal hypereosinophilic syndrome | HES-M | HES-N | Neoplastic hypereosinophilic syndrome | Primary HES
A rare hypereosinophilic syndrome characterized by hypereosinophilia produced by clonal eosinophils derived from neoplastic stem cells in the absence of any secondary cause of eosinophilia and persisting for at least six months. The condition is associated with signs of organ infiltration dysfunction and damage. Clinical manifestations are highly variable depending on the organ systems involved and include dermatologic pulmonary cardiac gastrointestinal and cerebral manifestations among others.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
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Primary hypereosinophilic syndrome?
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