Primary melanoma of the central nervous system
Synonyms: Malignant melanoma of meninges | Primary melanoma of the CNS
Primary melanoma of the central nervous system is a rare tumor of meninges arising from leptomeningeal melanocytes typically in the perimedullary or high cervical region in the absence of melanoma outside the CNS. The tumor is typically a darkly pigmented solid mass often containing hemorrhagic or necrotic areas composed of sheets of pleomorphic cells with prominent nucleoli with frequent mitotic figures and parenchymal invasion. Intracranial tumor may present with signs of raised intracranial pressure focal neurological symptoms related to tumor location seizures or subarachnoid hemorrhage spinal tumor may present with back pain muscle weakness numbness plegia or urinary incontinence.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
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Primary melanoma of the central nervous system?
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Advocacy Organizations
COMBINEDBrain Inc
COMBINEDBrain is a consortium for outcome measures and biomarkers for neurodevelopmental disorders. We are collaborating to cure rare, non-verbal brain disorders.
Help Hope Live
Help Hope Live assists individuals living with catastrophic injuries and illnesses to fundraise toward their medical expenses and related costs.
Moonshots for Unicorns
Curing single-gene disorders
My Faulty Gene
My Faulty Gene is a nonprofit organization which provides information and assistance to any individual whose family medical history suggests genetic testing might be helpful in identifying an increased risk of disease due to a genetic mutation. We believe that everyone in need of genetic testing should have access to it.
My Little Sunshine Foundation
My Little Sunshine is a non-profit foundation dedicated to educating people about the importance of fertility preservation and making fertility resources accessible to all.
Project CASK
To fund research for treatment and/or a cure for CASK Gene Disorder
SALUS
Educate and provide resources to POC with Rare Cancers
Clinical Trials
For a list of clinical trials in this disease area, please click here.