Shone complex

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Shone complex is a rare congenital cardiac malformation characterized by a complex of four obstructive lesions of the left heart: supravalvular mitral membrane parachute mitral valve muscular or membranous subvalvular aortic stenosis and coarctation of aorta. Clinical manifestations include heart murmur shortness of breath and increased load intolerance left ventricular hypertrophy and dilatation of the left atrium. Partial forms involving only two or three out of the four specific anomalies are also described and occasionally other cardiovascular anomalies (e.g. bicuspid aortic valve patent ductus arteriosus ventricular septal defect) may be associated.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version May 2024

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Shone complex?

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Clinical Trials

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