Synonyms: SMZL
Splenic marginal zone lymphoma is a rare indolent B-cell non-Hodgkin lymphoma characterized by abnormal clonal proliferation of mature B-lymphocytes with involvement in the spleen bone marrow and frequently the blood. It usually presents with splenomegaly lymphocytosis anemia and/or thrombocytopenia. Hepatitis C virus and autoimmune manifestations such as autoimmune hemolytic anemia and autoimmune thrombocytopenia could be associated.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version May 2026
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Splenic marginal zone lymphoma?
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Advocacy Organizations
RUNX1 Research Program
At the RUNX1 Research Program, our mission is to improve the quality of life and prevent cancer in patients with RUNX1-FPD. We do this by promoting awareness and funding world-class collaborative research with an empowered patient community.
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Clinical Trials
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