Synonyms: Undifferentiated esophageal carcinoma
A rare aggressive malignant epithelial carcinoma of the esophagus characterized macroscopically by an exophytic mass with central ulceration located on the esophagus and histologically by a sheet-like growth of neoplastic cells without significant glandular squamous or neuroendocrine differentiation. Patients may present with progressive dysphagia long-standing history of gastroesophageal reflux weight loss anemia abdominal or chest pain/pressure dyspnea and/or hematemesis. Presence or history of Barrett esophagus is frequently associated.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2026
Newly diagnosed with
Undifferentiated carcinoma of esophagus?
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Clinical Trials
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