Seronegative autoimmune hepatitis

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Seronegative autoimmune hepatitis

Synonyms: Autoantibody-negative autoimmune hepatitis | Seronegative AIH

A form of autoimmune hepatitis characterized by the features of classic autoimmune hepatitis (i. e. clinical presentation as acute or chronic cryptogenic hepatitis interface hepatitis on histological examination elevated serum aspartate aminotransferase and alanine aminotransferase levels hypergammaglobulinemia/elevated immunoglobulin G therapeutic response to corticosteroids) in the absence of serum autoantibodies. Clinical manifestations include fatigue malaise arthralgia jaundice at later stages also signs of advanced chronic liver disease such as spider nevi caput medusae splenomegaly ascites and palmar erythema. Presence of concurrent autoimmune diseases is frequently observed.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: // Data version September 2023.

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