Synonyms: AIH
A rare liver disease characterized by immune-mediated acute or chronic liver inflammation clinically presenting as cryptogenic hepatitis with interface hepatitis on histological examination elevated serum aminotransferase levels and hypergammaglobulinemia / elevated immunoglobulin G in the presence or absence of specific circulating autoantibodies. Patients may be asymptomatic chronically ill or present with acute liver failure. Concurrent autoimmune diseases are frequently observed.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version January 2026
Newly diagnosed with
Autoimmune hepatitis?
Our RARE Concierge Services Guides are available to assist you by providing information, resources and connections as you navigate your rare disease journey.
Advocacy Organizations
Global Liver Institute
To improve the lives of individuals and families impacted by liver disease through promoting innovation, encouraging collaboration, and scaling optimal approaches to help eradicate liver diseases.
Help Hope Live
Help Hope Live believes a medical crisis shouldn’t become a financial crisis. Help Hope Live supports community-based fundraising for people with unmet medical expenses and related costs due to cell and organ transplants or catastrophic injuries and illnesses. These efforts play a critical role in helping clients access the care and equipment they need to heal, live, and thrive.
Don't see your organization here. Let us know here.
Clinical Trials
For a list of clinical trials in this disease area, please click here.