Hallermann-Streiff-like syndrome
Synonyms: Dennis-Fairhurst-Moore syndrome | Hallermann-Streiff-François syndrome, severe form | Severe Hallermann-Streiff-François syndrome
A rare genetic bone development disorder characterized by multiple congenital fractures slender ribs and long bones deficient ossification of the skull and dysmorphic facial features reminiscent of Hallermann-Streiff syndrome (such as high forehead and triangular face with small jaw deep-set eyes beaked narrow nose downturned mouth and posteriorly angulated ears). Bilateral microphthalmia cataracts and pulmonary hypoplasia have also been reported. The disease is fatal in the neonatal period. There have been no further descriptions in the literature since 1995.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
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Hallermann-Streiff-like syndrome?
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Advocacy Organizations
DDX3X Foundation
Our mission is to connect families, resources, and the medical community to advance research for a treatment or cure to DDX3X Syndrome. Our ultimate goal is to accelerate brain function in individuals affected by DDX3X Syndrome through advances in cell and gene therapy and pharmaceuticals.
National Foundation for Ectodermal Dysplasias
The NFED mission is to empower and connect those touched by ectodermal dysplasias through education, support and research.
Clinical Trials
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