Twin-reversed arterial perfusion sequence
Synonyms: TRAP
A rare disorder related to monochorionic twin pregnancy characterized by complete or partial absence of cardiac development in one twin (”acardiac twin”) and blood supply of both circulations by the morphologically normal co-twin (”pump twin”) via an arterioarterial anastomosis. In most cases the acardiac twin has well developed legs and pelvis but no cephalic pole thoracic organs and upper extremities. The condition is associated with a high risk of perinatal death of the pump twin due to a combination of high-output cardiac failure and polyhydramnios-related pre-term birth. Hypoxia and intrauterine growth restriction are also seen in the pump twin.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version May 2024
Newly diagnosed with
Twin-reversed arterial perfusion sequence?
Our RARE Concierge Services Guides are available to assist you by providing information, resources and connections as you navigate your rare disease journey.
Advocacy Organizations
3G SARL
Our mission is to design and/or implement information and communication technology solutions in the healthcare field.
Clinical Trials
For a list of clinical trials in this disease area, please click here.