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Acute myelomonocytic leukemia

Overview

A rare acute myeloid leukemia disorder characterized by increased blast cells (myeloblasts monoblast and/or promonoblasts) representing more than 20% of the total bone marrow (BM) or peripheral blood differential counts with 20-80% of BM cells being of monocytic lineage. Clinical presentation is the result of bone marrow involvement and extramedullary infiltration by the leukemic cells and includes asthenia pallor fever dizziness respiratory symptoms easy bruising bleeding disorders and neurological deficits. Gingival hyperplasia organomegaly especially hepatosplenomegaly and lymphadenopathy may also be associated.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.

Reference: Access aggregated data from Orphanet at Orphadata.

Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version June 2022.

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