Type of disease: Rare conditions
Morgagni-Stewart-Morel (MSM) syndrome is a condition characterized by thickening of the frontal bone of the skull (hyperostosis frontalis interna), as well as obesity and excessive hair growth (hypertrichosis) in some individuals. Other signs and symptoms may include seizures, headaches, diabetes insipidus, and sex gland disturbances. The cause of Morgagni-Stewart-Morel syndrome is not fully understood. Some instances of dominant inheritance have been reported, but whether it is autosomal dominant or X-linked dominant is not known. Source: Genetic and Rare Diseases Information Center (GARD), supported by ORDR-NCATS and NHGRI.