T-B+ severe combined immunodeficiency due to CD3delta/CD3epsilon/CD3zeta
Synonyms: T-B+ SCID due to CD3delta/CD3epsilon/CD3zeta
A rare T-B+ severe combined immunodeficiency characterized by a T cell-negative B cell-positive natural killer (NK) cell-positive immune phenotype. Patients present in infancy or early childhood with recurrent infections. Clinical manifestations may vary in severity depending on the underlying molecular defect resulting in early death without bone marrow transplantation in some patients.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
Newly diagnosed with
T-B+ severe combined immunodeficiency due to CD3delta/CD3epsilon/CD3zeta?
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Clinical Trials
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