Acute liver failure
Synonyms: Acute hepatic failure | Fulminant hepatic failure
A rare hepatic disease characterized by acute onset of severe liver dysfunction without evidence of underlying chronic liver disease. Patients present with nonspecific symptoms like jaundice upper right abdominal pain nausea vomiting pruritus fatigue and fever. The condition may rapidly progress to hepatic encephalopathy coagulopathy and life-threatening multiorgan failure. Liver biopsy typically shows massive hepatic necrosis.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Reference: Access aggregated data from Orphanet at Orphadata.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version April 2024
Newly diagnosed with
Acute liver failure?
Our RARE Concierge Services Guides are available to assist you by providing information, resources and connections as you navigate your rare disease journey.
Advocacy Organizations
Global Liver Institute
To improve the lives of individuals and families impacted by liver disease through promoting innovation, encouraging collaboration, and scaling optimal approaches to help eradicate liver diseases.
Clinical Trials
For a list of clinical trials in this disease area, please click here.