Acute liver failure

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Synonyms: Acute hepatic failure | Fulminant hepatic failure

A rare hepatic disease characterized by acute onset of severe liver dysfunction without evidence of underlying chronic liver disease. Patients present with nonspecific symptoms like jaundice upper right abdominal pain nausea vomiting pruritus fatigue and fever. The condition may rapidly progress to hepatic encephalopathy coagulopathy and life-threatening multiorgan failure. Liver biopsy typically shows massive hepatic necrosis.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version June 2024

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Clinical Trials

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