A rare high-grade malignant glial tumor histologically characterized by abundance of pleomorphic astrocytes and multiple mitotic figures often associated with diffuse infiltration of the surrounding tissue considerable edema and mass effect and involvement of the contralateral brain. Depending on the primary localization of the tumor patients can present with signs of raised intracranial pressure (headache vomiting papilledema) seizures progressive neurological deficits and/or behavioral changes. The tumor is most commonly localized in the frontal and temporal lobes brain stem and spinal cord.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http: //www.orphadata.org. Data version September 2023.
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Curing single-gene disorders
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